Development and Validation of the Youth Pre-Exposure Prophylaxis (PrEP) Stigma Scale

Budhwani H., Yiğit İ., Maragh-Bass A. C., Rainer C. B., Claude K., Muessig K. E., ...More

AIDS AND BEHAVIOR, vol.27, no.3, pp.929-938, 2023 (SSCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 3
  • Publication Date: 2023
  • Doi Number: 10.1007/s10461-022-03829-9
  • Journal Name: AIDS AND BEHAVIOR
  • Journal Indexes: Social Sciences Citation Index (SSCI), Scopus, CINAHL, Criminal Justice Abstracts, Educational research abstracts (ERA), EMBASE, Gender Studies Database, MEDLINE, Psycinfo, Public Affairs Index, Social services abstracts, Sociological abstracts
  • Page Numbers: pp.929-938
  • Keywords: HIV, PrEP, Pre-Exposure Prophylaxis, Stigma, Men who have Sex with Men, MSM, Transgender Women, Scale Development, Scale Validation, HIV STIGMA, HEALTH, RISK, PREVENTION, MEN, SEX
  • TED University Affiliated: Yes


To date, there are no established scales to assess PrEP stigma among youth. We validated the Youth PrEP Stigma Scale within the Adolescent Trials Network P3 study (2019-2021). Data from sexual and gender minority youth (16-24 years) who were prescribed PrEP across nine domestic sites were evaluated (N = 235). Descriptive statistics, exploratory factor analysis, and correlation coefficients are reported. Results yielded a three-factor solution (PrEP Disapproval by Others, Enacted PrEP Stigma, and PrEP User Stereotypes) with strong factor loadings and Cronbach's alphas ranging from 0.83 to 0.90, suggesting excellent internal consistency. Correlations between this Scale, anticipated HIV stigma, perceived HIV risk, and disclosure of sexual identity were significant, indicating potential for robust application. Given the persistence of HIV infections among youth, stigma as a barrier to prevention, and expansion of PrEP modalities, the Youth PrEP Stigma Scale could enhance intervention and mechanistic research among youth at elevated risk for HIV acquisition.