Laser array beam propagation through liver tissue

Gökçe M. C., Baykal Y., Ata Y.

JOURNAL OF VISUALIZATION, vol.23, no.2, pp.331-338, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.1007/s12650-020-00630-5
  • Journal Name: JOURNAL OF VISUALIZATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, INSPEC
  • Page Numbers: pp.331-338
  • Keywords: Tissue turbulence, Optical wave propagation, Optical imaging, Effective beam spot radius, Optical intensity, INTENSITY, COHERENCE, INDEX, WAVE
  • TED University Affiliated: Yes

Abstract

Laser array beam propagating through mouse liver tissue is investigated. The turbulence power spectrum of the liver tissue is employed in the extended Huygens-Fresnel method to obtain an optical intensity profile and beam broadening at the observation point in biological liver tissue. Variations of the beam profile and the beam broadening are simulated based on the number of beamlets, source size, wavelength and the ring radius of the array. A biological tissue, illuminated by the laser array beam, exhibits different beam profiles and beam spot radius variations when the number of beamlets, source size, wavelength and the ring radius of the laser array beam are varied. Examining these variations observed in the propagated optical beam and comparing them with the test cases, abnormalities such as cancer and tumor in a biological liver tissue can be diagnosed.